High Range, Australia 
despair
dɪˈspɛː/
noun
noun: despair; plural noun: despairs

    1.
    the complete loss or absence of hope.
    "a voice full of self-hatred and despair"
    synonyms:    hopelessness, desperation, distress, anguish, pain, unhappiness; dejection, depression, despondency, disconsolateness, gloom, melancholy, melancholia, misery, wretchedness;
    disheartenment, discouragement, resignedness, forlornness, defeatism, pessimism
    "many parents feel pain and despair about their teenage children"
    antonyms:    hope, joy

verb
verb: despair; 3rd person present: despairs; past tense: despaired; past participle: despaired; gerund or present participle: despairing

    1.
    lose or be without hope.
    "we should not despair"
    synonyms:    lose hope, give up hope, abandon hope, give up, lose heart, be discouraged, be despondent, be demoralized, resign oneself, throw in the towel/sponge, quit, surrender; be pessimistic, look on the black side;
    archaicdespond
    "don't despair if you didn't win this time"
    hopeless, desperate, anguished, distressed, broken-hearted, heartbroken, grief-stricken, inconsolable, sorrowing, suicidal, in despair;
    dejected, depressed, despondent, disconsolate, gloomy, melancholy, miserable, wretched, desolate, forlorn;
    disheartened, discouraged, demoralized, devastated, downcast, resigned, defeatist, pessimistic;
    literarydolorous
    "her mother gave me a despairing look"
    antonyms:    cheerful, optimistic

Origin
Middle English: the noun via Anglo-Norman French from Old French desespeir ; the verb from Old French desperer, from Latin desperare, from de- ‘down from’ + sperare ‘to hope’.
Translate despair to
Use over time for: despair
  
OMG, I am not sure if I used the "desperate" correctly. I should not comment in English.
  
"He who has never hoped can never despair"

— George Bernard Shaw
  
:heart: We are thinking of you.